ABSTRACT
The aim of the study was to investigate the effect of a new anti-stress drug on protein and lipid metabolism in thecultivation and fattening of pigs. The experiment was carried out on 5 groups of pigs of Irish Landrace breed (4experimental and 1 control) with 10 heads in each in the period from 60 to 210 days of age. Animals of 1, 2, 3and 4 experimental groups daily during the entire period of rearing and fattening received lithium ascorbate inthe form of powder at a dose of 10, 5, 2 and 0.5 mg/kg of live weight, respectively. Weighing was carried outbefore the introduction of the drug, for the 4th month and before slaughter. Before setting the animals in theexperiment and on the 180th day of the experiment, blood samples were taken. Triacylglycerols, total protein andglobulins, and fractions of lipoproteins were determined in blood plasma. Acting on protein and lipid metabolism,lithium ascorbate activates the functions associated with the participation of α-, β - globulins in the transport oflipids, as well as in the performance of γ-globulins protective functions. Lithium ascorbate has a positive effecton lipid-cholesterol metabolism and, as a result, contributes to the increase in live weight and quality of meat.With the introduction of feed lithium ascorbate from the 60th day prior to slaughter at a dosage of 10, 5 and 2mg/kg of body weight, lithium ascorbate exhibits a pronounced adaptogenic and stress-protection properties,prevents the accumulation of lipoproteins of low and very low density and activates the production of high-densitylipoproteins. And in the control animals, it is is observed in the reverse reaction. The use of lithium ascorbateaffects protein synthesis. Given that γ-and β-globulins serve as raw materials for the production ofimmunoglobulins, it can be noted that the animals treated with lithium ascorbate had the best opportunities forhumoral specific protection for 180 days of experience, which contributes to the increase of nonspecific immunityand resistance. The revealed effects of lithium ascorbate indicate the prospects for the development of neweffective ways to increase stress resistance, nonspecific resistance and productivity of animals using drugs basedon organic lithium salts.